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Tri-GalNAc(OAc)3 (TFA)
$220 – $350
Products Details
Product Description
– Tri-GalNAc(OAc)3 TFA is a tri-GalNAc ligand that can be used for the synthesis of GalNAc-LYTAC. GalNAc-LYTAC engages the asialoglycoprotein receptor for targeted protein degradation. tri-GalNAc: triantenerrary N-acetylgalactosamine; LYTAC: lysosome-targeting chimera[1].
Web ID
– HY-148118A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C81H129F3N10O38
References
– [1]Ahn G, et al. LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation. Nat Chem Biol. 2021 Sep;17(9):937-946.
CAS Number
– 1159408-65-7
Molecular Weight
– 1907.93
Compound Purity
– 98.0
SMILES
– CC(O[C@@H]1[C@H]([C@@H](O[C@@H]([C@@H]1OC(C)=O)COC(C)=O)OCCCCC(NCCCNC(CCOCC(COCCC(NCCCNC(CCCCO[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)COC(C)=O)OC(C)=O)OC(C)=O)NC(C)=O)=O)=O)(N)COCCC(NCCCNC(CCCCO[C@H]3[C@@H]([C@H]([C@H]([C@H](O3)COC(C)=O)OC(C)=O)OC(C)=O)NC(C)=O)=O)=O)=O)=O)NC(C)=O)=O.OC(C(F)(F)F)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– LYTACs
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
