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Tri-GalNAc(OAc)3-Perfluorophenyl
$2,950
Only 1000 item(s) left in stock.
Products Details
Product Description
– Tri-GalNAc(OAc)3-Perfluorophenyl is a pentafluorophenyl modified Tri-GalNAc(OAc)3 (HY-148118), a tri-GalNAc ligand that can be used for the synthesis of GalNAc-LYTAC. GalNAc-LYTAC engages the asialoglycoprotein receptor for targeted protein degradation. tri-GalNAc: triantenerrary N-acetylgalactosamine; LYTAC: lysosome-targeting chimera[1].
Web ID
– HY-145368B
Storage Temperature
– -20°C (Powder, stored under nitrogen)
Shipping
– Blue Ice
Molecular Formula
– C99H151F5N10O44
References
– [1]Zhou Y, et al. Development of Triantennary N-Acetylgalactosamine Conjugates as Degraders for Extracellular Proteins. ACS Cent Sci. 2021 Mar 24;7(3):499-506.
Molecular Weight
– 2280.29
Compound Purity
– 95.0
SMILES
– O=C(CCOCCOCCOCCOCCOCCC(OC1=C(F)C(F)=C(F)C(F)=C1F)=O)NC(COCCC(NCCCNC(CCCCO[C@H](O[C@@H]2COC(C)=O)[C@@H]([C@H]([C@H]2OC(C)=O)OC(C)=O)NC(C)=O)=O)=O)(COCCC(NCCCNC(CCCCO[C@H](O[C@@H]3COC(C)=O)[C@@H]([C@H]([C@H]3OC(C)=O)OC(C)=O)NC(C)=O)=O)=O)COCCC(NCCCNC(CCCCO[C@H](O[C@@H]4COC(C)=O)[C@@H]([C@H]([C@H]4OC(C)=O)OC(C)=O)NC(C)=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO|DMSO : 50 mg/mL (ultrasonic)
Target
– LYTACs
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
