Tri-GalNAc-DBCO

SKU T77948-1 mg Category Brand:

798 CAD

Only 1000 item(s) left in stock.

Products Details

Product Description

– Tri-GalNAc-DBCO is a PIP-GalNAc coupling compound that binds ASGPR to drive protein down-regulation and target compounds for protein degradation via copper-free strain-promoted azide-alkyne cycloaddition coupled to azide on a non-specifically labeled antibody.

Web ID

– T77948

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C82H127N11O29

References

– Green Ahn, et al. LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation. Nat Chem Biol. 2021 Sep;17(9):937-946.

Molecular Weight

– C82H127N11O29

Compound Purity

– 0.9992

SMILES

– CC(=O)N[C@H]1C(OCCCCC(=O)NCCCCNC(=O)CCOCC(COCCC(=O)NCCCNC(=O)CCCCOC2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2NC(C)=O)(COCCC(=O)NCCCNC(=O)CCCCO[C@@H]2O[C@H](O)[C@H](O)[C@H](O)[C@H]2NC(C)=O)NC(=O)CCCCC(=O)N2Cc3ccccc3C#Cc3ccccc32)O[C@H](CO)[C@H](O)[C@@H]1O

Pathway

– PROTAC

Product type

– PROTAC

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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