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Tramiprosate
$50 – $114
Products Details
Product Description
– Tramiprosate (Homotaurine), an orally active and brain-penetrant natural amino acid found in various species of red marine algae. Tramiprosate binds to soluble Aβ and maintains Aβ in a non-fibrillar form. Tramiprosate is also a GABA analog and possess neuroprotection, anticonvulsion and antihypertension effects[1][2][3].
Web ID
– HY-14602
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C3H9NO3S
References
– [1]R G Fariello, et al. Homotaurine (3 aminopropanesulfonic acid; 3APS) protects from the convulsant and cytotoxic effect of systemically administered kainic acid. Neurology. 1982 Mar;32(3):241-5.|[2]Wu S et al. Tramiprosate protects neurons against ischemic stroke by disrupting the interaction between PSD95 and nNOS. Neuropharmacology. 2014 Aug;83:107-17.|[3]Francine Gervais, et al. Targeting soluble Abeta peptide with Tramiprosate for the treatment of brain amyloidosis. Neurobiol Aging. 2007 Apr;28(4):537-47.
CAS Number
– 3687-18-1
Molecular Weight
– 139.17
Compound Purity
– 98.0
SMILES
– NCCCS(=O)(O)=O
Clinical Information
– Phase 4
Research Area
– Cancer
Solubility
– DMSO : 1 mg/mL (ultrasonic)|H2O : 20 mg/mL (ultrasonic)
Target
– Amyloid-β
Pathway
– Neuronal Signaling
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
