TPCA-1

SKU T3049-2 mg Category Brand:

Price range: 61 CAD through 714 CAD

Products Details

Product Description

– TPCA-1 (TPCA1) is an effective and specific IKK-2 inhibitor (IC50: 17.9 nM); shows >22-fold selectivity over IKK-1 and >550-fold selectivity over others kinases and enzymes.

Web ID

– T3049

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C12H10FN3O2S

Citations

– 1. Luebke T, Schwarz L, Beer Y Y, et al. c-FLIP and CD95 signaling are essential for survival of renal cell carcinoma. Cell Death & Disease. 2019 May 16;10(6):384

References

– Podolin PL, et al, J Pharmacol Exp Ther, 2005, 312(1), 373-381.

CAS Number

– 507475-17-4

Molecular Weight

– C12H10FN3O2S

Compound Purity

– 0.9929

SMILES

– NC(=O)Nc1sc(cc1C(N)=O)-c1ccc(F)cc1

Pathway

– NF-κB|||JAK/STAT signaling|||Apoptosis|||Stem Cells

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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