TP-064
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TP-064

SKU T28996-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 51 CAD through 1,197 CAD

Products Details

Product Description

– TP-064 is a potent and selective PRMT4 inhibitor, featuring an IC50 < 10nM for methylation of H3 (1-25) and over 100-fold selectivity compared to other histone methyltransferases and non-epigenetic targets. It inhibits the methylation of MED12 in cells with an IC50 of 43 nM.

Web ID

– T28996

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C28H34N4O2

References

– Kazuhide Nakayama, et al. TP-064, a potent and selective small molecule inhibitor of PRMT4 for multiple myeloma. Oncotarget. 2018 Apr 6;9(26):18480-18493.

CAS Number

– 2080306-20-1

Molecular Weight

– C28H34N4O2

Compound Purity

– 0.9907

SMILES

– CNCCN1CCC(CC1)c1cc(CN(C)C(=O)c2cccc(Oc3ccccc3)c2)ccn1

Pathway

– Chromatin/Epigenetic

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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