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Tomatidine (hydrochloride)
$50 – $350
Products Details
Product Description
– Tomatidine hydrochloride acts as an anti-inflammatory agent by blocking NF-κB and JNK signaling[1]. Tomatidine hydrochloride activates autophagy either in mammal cells or C elegans[2].
Web ID
– HY-N2149A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C27H46ClNO2
References
– [1]Anil Ahsan, et al. Tomatidine Protects Against Ischemic Neuronal Injury by Improving Lysosomal Function. Eur J Pharmacol. 2020 Jun 21;173280.|[2]Chiu FL, et al. Tomatidine inhibits iNOS and COX-2 through suppression of NF-kappaB and JNK pathways in LPS-stimulated mouse macrophages. FEBS Lett. 2008 Jul 9;582(16):2407-12.
CAS Number
– 6192-62-7
Molecular Weight
– 452.11
Compound Purity
– 98.0
SMILES
– [H][C@]1(O[C@]2(NC[C@@H](C)CC2)[C@H]3C)C[C@@]4([H])[C@]5([H])CC[C@@]6([H])C[C@@H](O)CC[C@]6(C)[C@@]5([H])CC[C@]4(C)[C@]13[H].Cl[H]
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology; Cardiovascular Disease
Solubility
– DMSO : 5 mg/mL (ultrasonic;adjust pH to 9 with NaOH)|Ethanol : 3.45 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Autophagy;Endogenous Metabolite;JNK;NF-κB
Isoform
– JNK;RelA/p65
Pathway
– Autophagy;MAPK/ERK Pathway;Metabolic Enzyme/Protease;NF-κB
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
