TM-N1324
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TM-N1324

SKU T17103-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 70 CAD through 1,406 CAD

Products Details

Product Description

– TM-N1324 is a GPR39 agonist. TM-N1324 activates human GPR39 with high efficacy and potencies of 280 nM and 9 nM in the absence and presence of Zn2+, respectively. TM-N1324 has similar potencies to murine GPR39 with EC50s of 180 nM and 5 nM, respectively.

Web ID

– T17103

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H13ClFN7O

References

– Frimurer TM, et al. Model-Based Discovery of Synthetic Agonists for the Zn2+-Sensing G-Protein-Coupled Receptor 39 (GPR39) Reveals Novel Biological Functions. J Med Chem. 2017 Feb 9;60(3):886-898.

CAS Number

– 1144477-35-9

Molecular Weight

– C18H13ClFN7O

Compound Purity

– 0.9988

SMILES

– Cc1nn(c2NC(=O)CC(c12)c1ccc(F)cc1Cl)-c1ncnc2[nH]cnc12

Target

– Endogenous Metabolite

Pathway

– GPCR/G Protein

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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