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TLR7/8 agonist 4 hydroxy-PEG10-acid
SKU
HY-139018-Get quote
Category ADC Related
Tags Antibody-drug Conjugate/ADC Related, Cancer, Drug-Linker Conjugates for ADC
Products Details
Product Description
– TLR7/8 agonist 4 hydroxy-PEG10-acid (compound 9) is a agent-linker conjugate for ADC with potent antitumor activity by using TLR7/8 agonist 4 (HY-139018; a TLR7/8 agonist), linked via the cleavable ADC linker hydroxy-PEG10-acid (HY-133307)[1].
Web ID
– HY-139018
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C41H68N6O12
References
– [1]Shelley Erin ACKERMAN, et al. Immunoconjugates targeting her2. WO2020190725A1.
CAS Number
– 2388520-17-8
Molecular Weight
– 837.01
SMILES
– CCCCC(NC1=C2C(C=CC(N(CC3)CCN3CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)=C2)=N4)=NC1=C4N
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Drug-Linker Conjugates for ADC
Isoform
– Traditional Cytotoxic Agents
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.