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TLR7/8 agonist 4 hydroxy-PEG10-acid

Products Details

Product Description

– TLR7/8 agonist 4 hydroxy-PEG10-acid (compound 9) is a agent-linker conjugate for ADC with potent antitumor activity by using TLR7/8 agonist 4 (HY-139018; a TLR7/8 agonist), linked via the cleavable ADC linker hydroxy-PEG10-acid (HY-133307)[1].

Web ID

– HY-139018

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C41H68N6O12

References

– [1]Shelley Erin ACKERMAN, et al. Immunoconjugates targeting her2. WO2020190725A1.

CAS Number

– 2388520-17-8

Molecular Weight

– 837.01

SMILES

– CCCCC(NC1=C2C(C=CC(N(CC3)CCN3CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)=C2)=N4)=NC1=C4N

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Drug-Linker Conjugates for ADC

Isoform

– Traditional Cytotoxic Agents

Pathway

– Antibody-drug Conjugate/ADC Related

Product type

– ADC Related

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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