Tipiracil (hydrochloride)

$66$343

Products Details

Product Description

– Tipiracil (hydrochloride) is a thymidine phosphorylase inhibitor (TPI), used for cancer research.

Web ID

– HY-A0063

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C9H12Cl2N4O2

Citations

– Biomed Pharmacother. 2021 May 6;139:111672.|J Mol Med (Berl). 2019 Aug;97(8):1183-1193.|Mod Rheumatol. 2018 May;28(3):495-505.|Patent. US Patent 11110111.|Oncol Rep. 2023 Mar;49(3):52.

References

– [1]Peters GJ, et al. TAS-102: more than an antimetabolite. Lancet Oncol. 2012 Dec;13(12):e518-9.|[2]Yoshino T, et al. TAS-102 monotherapy for pretreated metastatic colorectal cancer: a double-blind, randomised, placebo-controlled phase 2 trial. Lancet Oncol. 2012 Oct;13(10):993-1001.

CAS Number

– 183204-72-0

Molecular Weight

– 279.12

Compound Purity

– 99.99

SMILES

– [H]Cl.O=C1C(Cl)=C(CN2C(CCC2)=N)NC(N1)=O

Clinical Information

– Launched

Research Area

– Cancer

Solubility

– H2O : 50 mg/mL (ultrasonic)

Target

– Nucleoside Antimetabolite/Analog

Pathway

– Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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