Tipifarnib
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Tipifarnib

SKU T6271-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 54 CAD through 733 CAD

Products Details

Product Description

– Tipifarnib (IND 58359) is a nonpeptidomimetic quinolinone with potential antineoplastic activity. Tipifarnib binds to and inhibits the enzyme farnesyl protein transferase, an enzyme involved in protein processing (farnesylation) for signal transduction. By inhibiting the farnesylation of proteins, this agent prevents the activation of Ras oncogenes, inhibits cell growth, induces apoptosis, and inhibits angiogenesis.

Web ID

– T6271

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C27H22Cl2N4O

References

– Margolin KA, et al. Clin Cancer Res. 2012, 18(4), 1129-1137.

CAS Number

– 192185-72-1

Molecular Weight

– C27H22Cl2N4O

Compound Purity

– 0.9922

SMILES

– Cn1cncc1[C@@](N)(c1ccc(Cl)cc1)c1ccc2n(C)c(=O)cc(-c3cccc(Cl)c3)c2c1

Pathway

– Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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