THP-PEG6-OH

$40$110

Products Details

Product Description

– THP-PEG6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. THP-PEG6-OH is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].

Web ID

– HY-126918

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C17H34O8

References

– [1]Masahiro Tomita, et al. Antibody specifically recognizing resin plasticizer compound. WO2005105846A1.|[2]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

CAS Number

– 42607-87-4

Molecular Weight

– 366.45

Compound Purity

– 95.0

SMILES

– OCCOCCOCCOCCOCCOCCOC1CCCCO1

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– ADC Linker;PROTAC Linkers

Isoform

– Non-cleavable Linker;PEG Linkers

Pathway

– Antibody-drug Conjugate/ADC Related;PROTAC

Product type

– ADC Related

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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