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THP-PEG6-OH
SKU
HY-126918-100 mg
Category ADC Related
Tags ADC Linker;PROTAC Linkers, Antibody-drug Conjugate/ADC Related;PROTAC, Cancer
$40 – $110
Products Details
Product Description
– THP-PEG6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. THP-PEG6-OH is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].
Web ID
– HY-126918
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C17H34O8
References
– [1]Masahiro Tomita, et al. Antibody specifically recognizing resin plasticizer compound. WO2005105846A1.|[2]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
CAS Number
– 42607-87-4
Molecular Weight
– 366.45
Compound Purity
– 95.0
SMILES
– OCCOCCOCCOCCOCCOCCOC1CCCCO1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Linker;PROTAC Linkers
Isoform
– Non-cleavable Linker;PEG Linkers
Pathway
– Antibody-drug Conjugate/ADC Related;PROTAC
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.