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Products Details
Product Description
– C-11 is a tubulin inhibitor and acts as an ADC cytotoxin, displays cytotoxicity for carcinoma cell lines[1].
Web ID
– HY-100861
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C38H58N6O7S
References
– [1]Leverett CA, et al. Design, Synthesis, and Cytotoxic Evaluation of Novel Tubulysin Analogues as ADC Payloads. ACS Med Chem Lett. 2016 Aug 26;7(11):999-1004.
CAS Number
– 2007965-97-9
Molecular Weight
– 742.97
SMILES
– O=C(N(C)[C@@H](C(C)C)C[C@@H](OC(C)=O)C1=NC(C(N[C@@H](CC2=CC=C(N)C=C2)C[C@H](C)C(O)=O)=O)=CS1)[C@H]([C@@H](C)CC)NC([C@@]3(C)CCCN3C)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Cytotoxin;Microtubule/Tubulin
Isoform
– Traditional Cytotoxic Agents
Pathway
– Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Cytoskeleton
Product type
– ADC Related
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
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