Thiocolchicine

SKU T41248-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 64 CAD through 547 CAD

Products Details

Product Description

– Thiocolchicine is an effective inhibitor of tubulin polymerization with an IC50 of 2.5 µM and a Ki of 0.7 µM. Thiocolchicine induces cell apoptosis. Thiocolchicine can be used as an ADC cytotoxin in ADC technology.

Web ID

– T41248

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H25NO5S

References

– R De Vincenzo, et al. Antiproliferative Activity of Colchicine Analogues on MDR-positive and MDR-negative Human Cancer Cell Lines. Anticancer Drug Des. 1998 Jan;13(1):19-33.

CAS Number

– 2730-71-4

Molecular Weight

– C22H25NO5S

Compound Purity

– 0.9819

SMILES

– COc1cc2CC[C@H](NC(C)=O)c3cc(=O)c(SC)ccc3-c2c(OC)c1OC

Pathway

– Cytoskeletal Signaling

Product type

– PROTAC

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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