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Products Details
Product Description
– Thalidomide-propargyl, a Thalidomide-derived Cereblon ligand, facilitates the recruitment of Cereblon. It can be attached to the protein ligand via a linker, producing IMiD-containing PROTACs.
Web ID
– T18831
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C16H12N2O5
References
– Wurz RP, et al. A “Click Chemistry Platform” for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation. J Med Chem. 2018 Jan 25;61(2):453-461.
CAS Number
– 2098487-39-7
Molecular Weight
– C16H12N2O5
Compound Purity
– 0.9514
SMILES
– O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2OCC#C
Target
– Dehydrogenase
Pathway
– PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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