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Thalidomide-Piperazine 5-fluoride
SKU
HY-134983-Get quote
Category Reference compound
Tags Cancer, E3 Ligase Ligand-Linker Conjugates, PROTAC
Products Details
Product Description
– Thalidomide-Piperazine 5-fluoride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
Web ID
– HY-134983
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C17H17FN4O4
References
– [1]Hexiang Wang, et al. Degradation of androgen receptor (ar) by conjugation of ar antagonists with e3 ligase ligand and methods of use. WO2021058017A1.
CAS Number
– 2222114-22-7
Molecular Weight
– 360.34
SMILES
– O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=C(N4CCNCC4)C(F)=C3)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– E3 Ligase Ligand-Linker Conjugates
Pathway
– PROTAC
Product type
– Reference compound
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