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Thalidomide-O-C8-COOH
$680 – $1,800
Products Details
Product Description
– Thalidomide-O-C8-COOH is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-O-C8-COOH (Cereblon ligand 3) can be connected to the ligand for protein by a linker to form PROTACs[1].
Web ID
– HY-130952
Storage Temperature
– -20°C (Powder, stored under nitrogen)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C22H26N2O7
References
– [1]Nathanael S. Gray, et al. Degraders of wee1 kinase. WO2020069105A1.
CAS Number
– 2225148-51-4
Molecular Weight
– 430.45
Compound Purity
– 97.44
SMILES
– O=C(O)CCCCCCCCOC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 140 mg/mL (ultrasonic)
Target
– Ligands for E3 Ligase
Isoform
– Cereblon
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
