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Thalidomide-O-amido-PEG4-C2-NH2 (hydrochloride)
$50 – $450
Products Details
Product Description
– Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1].
Web ID
– HY-122710A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H35ClN4O10
References
– [1]James Bradner, et al. Methods to induce targeted protein degradation through bifunctional molecules. WO2016105518A1.
CAS Number
– 2245697-85-0
Molecular Weight
– 587.02
Compound Purity
– 95.0
SMILES
– O=C(NCCOCCOCCOCCOCCN)COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– E3 Ligase Ligand-Linker Conjugates
Isoform
– Cereblon
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
