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Products Details
Product Description
– Thalidomide-O-amido-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 3) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
Web ID
– HY-107440
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C23H30N4O9
References
– [1]Methods to induce targeted protein degradation through bifunctional molecules. WO 2017007612 A1
CAS Number
– 1957236-20-2
Molecular Weight
– 506.51
SMILES
– NCCOCCOCCOCCNC(COC1=C(C2=CC=C1)C(N(C(CCC3=O)C(N3)=O)C2=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– E3 Ligase Ligand-Linker Conjugates
Isoform
– Cereblon
Pathway
– PROTAC
Product type
– Reference compound
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