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Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc
$280 – $720
Products Details
Product Description
– Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc incorporates the Thalidomide based cereblon ligand and a linker. Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc can be used for the synthesis of PROTAC BET degrader[1]. (From patent WO2017180417A1 compound s7).
Web ID
– HY-145177
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C30H42N4O11
References
– [1]Shaomeng Wang, et al. Bet protein degraders. WO2017180417A1.
CAS Number
– 1799711-31-1
Molecular Weight
– 634.67
Compound Purity
– 98.43
SMILES
– O=C(NCCCOCCOCCOCCCNC(COC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)=O)OC(C)(C)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– E3 Ligase Ligand-Linker Conjugates
Isoform
– Cereblon
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
