Thalidomide-NH-PEG7
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Thalidomide-NH-PEG7

SKU T18814-100 mg Category Brand:

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Products Details

Product Description

– Thalidomide-NH-PEG7 is a synthesized conjugate of an E3 ligase ligand and linker, intended for use in antibody-drug conjugates (ADCs). It can be attached to a protein ligand via a linker to form PROTAC iRucaparib-AP6, a highly selective degrader of PARP1[1].

Web ID

– T18814

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C27H39N3O11

References

– Wang S, et al. Uncoupling of PARP1 trapping and inhibition using selective PARP1 degradation.Nat Chem Biol. 2019 Dec;15(12):1223-1231.

Molecular Weight

– C27H39N3O11

SMILES

– OCCOCCOCCOCCOCCOCCOCCNC1=CC=CC(C(N2C3CCC(NC3=O)=O)=O)=C1C2=O

Target

– Others

Pathway

– Others

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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