Thalidomide-NH-PEG4-Ms

SKU T39604-100 mg Category Brand:

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Products Details

Product Description

– Thalidomide-NH-PEG4-Ms is a conjugate that consists of a cereblon ligand based on Thalidomide and a linker molecule, which serves as a ligand-linker moiety for E3 ligase. This conjugate is specifically designed as a degrader for PROTAC BCL-XL, known as XZ739.

Web ID

– T39604

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H29N3O10S

References

– Xuan Zhang,et al. Discovery of PROTAC BCL-X L Degraders as Potent Anticancer Agents With Low On-Target Platelet Toxicity. Eur J Med Chem. 2020 Apr 15;192:112186.

CAS Number

– 2140807-24-3

Molecular Weight

– C22H29N3O10S

SMILES

– CS(=O)(=O)OCCOCCOCCOCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12

Pathway

– Others

Product type

– PROTAC

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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