Thalidomide-NH-PEG2-C2-NH-Boc

SKU T39524-50 mg Category Brand:

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Products Details

Product Description

– Thalidomide-NH-PEG2-C2-NH-Boc, a synthesized E3 ligase ligand-linker conjugate, combines the cereblon-targeting Thalidomide ligand with a PEG linker for the synthesis of dBRD9 (compound 6). This selective BRD9 probe PROTAC degrader is utilized in researching BAF complex biology.

Web ID

– T39524

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C24H32N4O8

References

– David Remillard, et al. Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands.2017 May 15;56(21):5738-5743.

CAS Number

– 2097509-40-3

Molecular Weight

– C24H32N4O8

SMILES

– O=C(OC(C)(C)C)NCCOCCOCCNC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3

Pathway

– Others

Product type

– PROTAC

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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