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Thalidomide-5-NH-PEG1-NH2 (hydrochloride)
Products Details
Product Description
– Thalidomide-5-NH-PEG1-NH2 hydrochloride is a Thalidomide (HY-14658)-based cereblon ligand that recruits CRBN proteins. Thalidomide-5-NH-PEG1-NH2 hydrochloride can be connected to the target protein ligand through a linker to form a PROTAC molecule. For example, THAL-SNS-032 (HY-123937).
Web ID
– HY-156163
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture and light)
Shipping
– Blue Ice
Molecular Formula
– C17H21ClN4O5
CAS Number
– 2863634-98-2
Molecular Weight
– 396.83
Compound Purity
– 98.87
SMILES
– O=C1NC(C(CC1)N2C(C3=CC=C(NCCOCCN)C=C3C2=O)=O)=O.Cl
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– Ligands for E3 Ligase
Pathway
– PROTAC
Product type
– Reference compound
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