Thalidomide-5-methyl

SKU HY-139548-1mg Category Tags , ,

$316

Only 1000 item(s) left in stock.

Products Details

Product Description

– Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein[1].

Web ID

– HY-139548

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C14H12N2O4

References

– [1]George W. Muller, et al. Substituted 2-(2,6 dioxo-3-fluoropiperidin-3-yl)-isoindolines and method of reducing TNFα levels. Patent US5874448A.

CAS Number

– 40313-92-6

Molecular Weight

– 272.26

SMILES

– O=C1NC(C(CC1)N2C(C3=CC=C(C)C=C3C2=O)=O)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Ligands for E3 Ligase

Pathway

– PROTAC

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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