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Products Details
Product Description
– Thalidomide 4-fluoride (E3 ligase Ligand 4) (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand. Thalidomide 4-fluoride can be used in the recruitment of CRBN protein. Thalidomide 4-fluoride (Cereblon ligand 4) can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1.
Web ID
– T7755
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C13H9FN2O4
References
– Nello Mainolfi, et al. Irak degraders and uses thereof. US20190192668A1.
CAS Number
– 835616-60-9
Molecular Weight
– C13H9FN2O4
Compound Purity
– 0.9912
SMILES
– O=C1N(C(=O)C=2C1=CC=CC2F)C3C(=O)NC(=O)CC3
Pathway
– NF-κB|||Immunology/Inflammation|||PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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