Download Files:
Thalidomide 4-fluoride
$30 – $100
Products Details
Product Description
– Thalidomide 4-fluoride (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide 4-fluoride (Cereblon ligand 4) can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1 (HY-129966)[1].
Web ID
– HY-41547
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C13H9FN2O4
References
– [1]Nello Mainolfi, et al. Irak degraders and uses thereof. US20190192668A1.
CAS Number
– 835616-60-9
Molecular Weight
– 276.22
Compound Purity
– 99.94
SMILES
– O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3F)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 300 mg/mL (ultrasonic)
Target
– Ligands for E3 Ligase
Isoform
– Cereblon
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
