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Product Description
– Thalidomide (Thalomid) is a synthetic derivative of glutamic acid (alpha-phthalimido-glutarimide) with teratogenic, immunomodulatory, anti-inflammatory and anti-angiogenic properties.
Web ID
– T0213
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C13H10N2O4
Citations
– 1. Lü Z, Li X, Li K, et al. Nitazoxanide and related thiazolides induce cell death in cancer cells by targeting the 20S proteasome with novel binding modes. Biochemical Pharmacology. 2022: 114913.
2. Guo Y, Fan Y, Pei X. Fangjihuangqi Decoction inhibits MDA‐MB‐231 cell invasion in vitro and decreases tumor growth and metastasis in triple‐negative breast cancer xenografts tumor zebrafish model. Cancer Medicine. 2020, 9(7): 2564-2578.
3. Li P, Hu X, Fan Z, et al.Novel potent molecular glue degraders against broad range of hematological cancer cell lines via multiple neosubstrates degradation.Journal of Hematology & Oncology.2024, 17(1): 77.
References
– D’Amato RJ, et al. Proc Natl Acad Sci U S A, 1994, 91(9), 4082-4085.
CAS Number
– 50-35-1
Molecular Weight
– C13H10N2O4
Compound Purity
– 0.9988
SMILES
– O=C1N(C2CCC(=O)NC2=O)C(=O)c2ccccc12
Target
– Others
Pathway
– Apoptosis|||Autophagy|||PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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