Tetrazine-Ph-NHCO-PEG4-alkyne

SKU HY-133464-Get quote Category Tags , ,

Products Details

Product Description

– Tetrazine-Ph-NHCO-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Tetrazine-Ph-NHCO-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Web ID

– HY-133464

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C21H27N5O5

References

– [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Weight

– 429.47

SMILES

– O=C(NCC1=CC=C(C2=NN=CN=N2)C=C1)CCOCCOCCOCCOCC#C

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– PROTAC Linkers

Isoform

– PEG Linkers

Pathway

– PROTAC

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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