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Tesevatinib
Price range: 174 CAD through 1,728 CAD
Products Details
Product Description
– Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor with IC50 values of 0.3, 16, 1.5, 8.7, and 1.4 nM for EGFR, ErbB2, KDR, Flt4, and EphB4.
Web ID
– TQ0166
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H25Cl2FN4O2
References
– Gendreau SB, et al. Inhibition of the T790M gatekeeper mutant of the epidermal growth factor receptor by EXEL-7647. Clin Cancer Res. 2007 Jun 15;13(12):3713-23.
CAS Number
– 781613-23-8
Molecular Weight
– C24H25Cl2FN4O2
Compound Purity
– 0.9789
SMILES
– COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@H]1C[C@H]2CN(C)C[C@H]2C1
Pathway
– Angiogenesis|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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