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Terreic acid
SKU
HY-110013-5 mg
Category Reference compound
Tags Anti-infection;Protein Tyrosine Kinase/RTK, Antibiotic;Btk, Infection; Inflammation/Immunology
$820
Only 1000 item(s) left in stock.
Products Details
Product Description
– Terreic acid, a quinone epoxide antibiotic, acts as an effective Btk inhibitor. Terreic acid blocks the interaction between PKC and the pleckstrin homology domain of Btk. Terreic acid inhibits the binding of GST-BtkPH to PKC in lysates of HMC-1 human mast cells with an IC50 of approximately 100 μM[1].
Web ID
– HY-110013
Storage Temperature
– -20°C (Powder, protect from light)
Shipping
– Blue Ice
Applications
– COVID-19-anti-virus
Molecular Formula
– C7H6O4
References
– [1]Y Kawakami, et al. Terreic acid, a quinone epoxide inhibitor of Bruton’s tyrosine kinase. Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2227-32.
CAS Number
– 121-40-4
Molecular Weight
– 154.12
Compound Purity
– 99.0
SMILES
– O=C1[C@@H]2[C@H](C(C(O)=C1C)=O)O2
Clinical Information
– No Development Reported
Research Area
– Infection; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Antibiotic;Btk
Pathway
– Anti-infection;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.