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Tedizolid
$110 – $470
Products Details
Product Description
– Tedizolid (TR 700; Torezolid; DA-7157) is a novel oxazolidinone, acting through inhibition of bacterial protein synthesis by binding to 23S ribosomal RNA (rRNA) of the 50S subunit of the ribosome.
Web ID
– HY-14855
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C17H15FN6O3
Citations
– Antimicrob Agents Chemother. 2023 Jan 23;e0145922.|Antimicrob Agents Chemother. 2023 Mar 15;e0165522.|Front Microbiol. 2018 Sep 7;9:2095. |Infect Dis Rep. 2021, 13(3), 843-854.|J Antimicrob Chemother. 2021 Jan 19;76(2):292-296.|J Pharm Biomed Anal. 2016 Feb 20;120:402-12. |J Pharm Biomed Anal. 2017 May 30;139:221-231. |J Pharm Biomed Anal. 2019 May 30;169:170-180.|J Pharmaceut Biomed. 2021 Feb 5;194:113783.|Journal of Molecular Structure. 2016 Jul 5; 1115:136-143.|Nat Commun. 2023 Jun 22;14(1):3705.|Research Square Preprint. 2020 Jun.|TJPS (Thai Journal of Pharmaceutical Sciences). 2016;40(4):1-5.|J Pharm Biomed Anal. 2017 May 30;139:221-231. |J Pharm Health Care Sci. 2023 Nov 14;9(1):37.
References
– [1]Choi S, et al.
Activity of Tedizolid Phosphate (TR-701) in Murine Models of Infection with Penicillin-resistant and Penicillin-sensitive Streptococcus pneumoniae.
Antimicrob Agents Chemother. 2012 Jun 19.
CAS Number
– 856866-72-3
Molecular Weight
– 370.34
Compound Purity
– 99.19
SMILES
– O=C1O[C@@H](CO)CN1C2=CC=C(C3=CC=C(C4=NN(C)N=N4)N=C3)C(F)=C2
Clinical Information
– Launched
Research Area
– Infection
Solubility
– DMSO : 10 mg/mL (ultrasonic)
Target
– Antibiotic;Bacterial
Isoform
– Oxazolidinone
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.