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Products Details
Product Description
– TAME (Tosyl-Arginine Methyl Este), an inhibitor of the late-promoting complex (APC/C or APC), inhibits APC-dependent protein hydrolysis by competing for APC binding with the C-terminal isoleucine-arginine tail of the APC activator cytokinesis cycle 20 (Cdc20). TAME binds to and prevents APC binding by Cdc20 and Cdh20. TAME binds to APC and prevents its activation by Cdc20 and Cdh1.
Web ID
– T6693
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C14H22N4O4S
References
– Zeng X, et al. Cancer Cell, 2010, 18(4), 382-395.
CAS Number
– 901-47-3
Molecular Weight
– C14H22N4O4S
SMILES
– S(N[C@@H](CCCNC(=N)N)C(OC)=O)(=O)(=O)C1=CC=C(C)C=C1
Pathway
– Cell Cycle/Checkpoint
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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