Talniflumate

SKU T4503-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 48 CAD through 1,006 CAD

Products Details

Product Description

– Talniflumate (Somalgen) is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture. It possesses anti-inflammatory actions via inhibition of Cox (cyclooxygenase) and inhibits Cl-/HCO3- exchange activity. It also increases survival in a cystic fibrosis mouse model of the distal intestinal obstructive syndrome.

Web ID

– T4503

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H13F3N2O4

References

– Knight D. Talniflumate (Genaera)[J]. Current Opinion in Investigational Drugs, 2004, 5(5):557-62.

CAS Number

– 66898-62-2

Molecular Weight

– C21H13F3N2O4

Compound Purity

– 0.9993

SMILES

– O(C(=O)C1=C(NC2=CC(C(F)(F)F)=CC=C2)N=CC=C1)C3C=4C(C(=O)O3)=CC=CC4

Pathway

– Metabolism|||Immunology/Inflammation|||Membrane transporter/Ion channel|||Neuroscience

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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