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Products Details
Product Description
– SZUH280 is a potent, selective PROTAC (proteolysis targeting chimera) HDAC8 (histone deacetylase 8) degrader, demonstrating a DC50 of 0.58 μM in A549 cells. It induces apoptosis in cancer cells and impedes DNA damage repair, thereby enhancing cellular radiosensitization [1].
Web ID
– T75021
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C36H34N8O8
CAS Number
– 2770263-77-7
Molecular Weight
– C36H34N8O8
SMILES
– N(CC1=CN(CCOCCOC2=CC=C(CN3C=4C(C=C3)=CC=C(C(NO)=O)C4)C=C2)N=N1)C5=C6C(C(=O)N(C6=O)C7C(=O)NC(=O)CC7)=CC=C5
Pathway
– Others
Product type
– PROTAC
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