SYN1143
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SYN1143

SKU T8409-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 48 CAD through 285 CAD

Products Details

Product Description

– SYN1143 (AMG-1) is a potent inhibitor of human RON and c-Met.In vitro kinase assays showed that compound I is a potent inhibitor of human RON and c-Met with IC50s of 9 and 4 nmol/L, respectively.

Web ID

– T8409

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C31H29FN4O5

References

– Zhang Y, et, al. Identification of a novel recepteur d’origine nantais/c-met small-molecule kinase inhibitor with antitumor activity in vivo. Cancer Res. 2008 Aug 15;68(16):6680-7.

CAS Number

– 913376-84-8

Molecular Weight

– C31H29FN4O5

Compound Purity

– 0.9886

SMILES

– COc1ccc2c(Oc3ccc(NC(=O)c4c(C)n(CC(C)(C)O)n(-c5ccccc5)c4=O)cc3F)ccnc2c1

Pathway

– Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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