SY-5609

SKU T36038-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 227 CAD through 933 CAD

Products Details

Product Description

– SY-5609 (CDK7-IN-3) is a selective non-covalent CDK7 inhibitor (Kd value is 0.07 nM), with weak inhibitory activity against CDK2, CDK9 and CDK12 with IC50 values ​​of 5.5, 1.9 and 1.7 μM, respectively, and has anti-tumor activity and inhibits cell apoptosis.

Web ID

– T36038

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C23H26F3N6OP

References

– Michael Bradley, et al. Inhibitors of cyclin-dependent kinase 7 (cdk7). WO2020093011A1.

CAS Number

– 2417302-07-7

Molecular Weight

– C23H26F3N6OP

Compound Purity

– 0.9934

SMILES

– C(F)(F)(F)C=1C(C=2C=3C(NC2)=C(P(C)(C)=O)C(C#N)=CC3)=NC(N[C@H]4CCC(C)(C)NC4)=NC1

Pathway

– Cell Cycle/Checkpoint

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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