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Products Details
Product Description
– SW02 is a potent activator of ATPase activity of Hsp70, with an EC50 of 150 μM. SW02 leads to accumulation of both total tau and phosphorylated tau (pTau)[1].
Web ID
– HY-138820
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C19H23BrN2O5
References
– [1]Jinwal UK, et al. Chemical manipulation of hsp70 ATPase activity regulates tau stability. J Neurosci. 2009 Sep 30;29(39):12079-88.
CAS Number
– 1010820-68-4
Molecular Weight
– 439.30
SMILES
– O=C(OC)CCCN1C(C)=C(C(OCC)=O)C(C2=CC=C(Br)C=C2)NC1=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– HSP
Isoform
– HSP70
Pathway
– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
