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Surfen (dihydrochloride)
$105 – $950
Products Details
Product Description
– Surfen dihydrochloride is a potent HS (heparan sulfate) antagonist. Surfen binds to glycosaminoglycans. Surfen neutralizes the anticoagulant activity of both unfractionated and low molecular weight heparins. Surfen affects sulfation of heparin and inhibits degradation by heparin lyases. Surfen inhibits FGF2 binding and signaling. Surfen inhibits cell attachment, and virus infection[1].
Web ID
– HY-122704A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C21H22Cl2N6O
References
– [1]Schuksz M, et al. Surfen, a small molecule antagonist of heparan sulfate. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):13075-80.
CAS Number
– 5424-37-3
Molecular Weight
– 445.34
Compound Purity
– 99.0
SMILES
– O=C(NC1=CC=C2N=C(C)C=C(N)C2=C1)NC3=CC=C4N=C(C)C=C(N)C4=C3.[H]Cl.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– H2O : 8 mg/mL (ultrasonic;warming)
Target
– FGFR;HSV;VEGFR
Isoform
– FGFR2;HSV-1
Pathway
– Anti-infection;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
