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Product Description
– Surfen dihydrochloride (Aminoquinuride dihydrochloride) is a potent small molecule antagonist of heparin sulfate with antibacterial and antiviral activity, and inhibits anthrax lethal factor, coagulation factor X, and lethal factor.Surfen inhibits the anticoagulant activity of both normal and low-molecular-weight heparin and inhibits heparin sulfation and heparin cleavage enzyme degradation.Surfen inhibits the blockade of FGF2 binding and signaling mediated by heparin acetylsulfate. Surfen inhibits the blockade of acetylheparin sulfate-mediated FGF2 binding and signaling.Surfen inhibits SEVI and semen-mediated enhancement of HIV type 1 infection.
Web ID
– T26240
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C21H22Cl2N6O
References
– Schuksz M, et al. Surfen, a small molecule antagonist of heparan sulfate. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):13075-80.
CAS Number
– 5424-37-3
Molecular Weight
– C21H22Cl2N6O
Compound Purity
– 0.9708
SMILES
– Cl.Cl.Cc1cc(N)c2cc(NC(=O)Nc3ccc4nc(C)cc(N)c4c3)ccc2n1
Pathway
– Tyrosine Kinase/Adaptors|||Immunology/Inflammation|||Microbiology/Virology|||Angiogenesis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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