Sunitinib Malate

SKU T0374-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 48 CAD through 181 CAD

Products Details

Product Description

– Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor. It blocks the tyrosine kinase activities of VEGFR2, PDGFRβ (IC50: 80/2 nM), and c-kit.

Web ID

– T0374

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C26H33FN4O7

References

– Sun L, et al. Discovery of 5-[5-fluoro-2-oxo-1,2- dihydroindol-(3Z)-ylidenemethyl]-2,4- dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide, a novel tyrosine kinase inhibitor targeting vascular endothelial and platelet-derived growth factor receptor tyrosine kinase. J Med Chem. 2003 Mar 27;46(7):1116-9.

CAS Number

– 341031-54-7

Molecular Weight

– C26H33FN4O7

Compound Purity

– 0.9926

SMILES

– O[C@@H](CC(O)=O)C(O)=O.CCN(CC)CCNC(=O)c1c(C)[nH]c(C=C2/C(=O)Nc3ccc(F)cc23)c1C

Target

– Apoptosis|||Antibacterial|||Hydrogenase|||Antifection|||Parasite|||NADPH|||Antibiotic

Pathway

– Tyrosine Kinase/Adaptors|||Apoptosis|||Cell Cycle/Checkpoint|||Angiogenesis|||Autophagy

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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