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Sumanirole (maleate)
$83 – $1,012
Products Details
Product Description
– Sumanirole maleate (U-95666E; PNU-95666E) is a highly selective D2 receptor full agonist with an ED50 of about 46 nM. Sumanirole was developed for the treatment of Parkinson’s disease and restless leg syndrome.
Web ID
– HY-70081A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C15H17N3O5
References
– [1]Arthur G. Romero, et al. Synthesis of the Selective D2 Receptor Agonist PNU-95666E from
D-Phenylalanine Using a Sequential Oxidative Cyclization
Strategy. J. Org. Chem. 1997, 62, 6582-6587
CAS Number
– 179386-44-8
Molecular Weight
– 319.31
Compound Purity
– 99.0
SMILES
– O=C1NC2=C3N1C[C@H](NC)CC3=CC=C2.O=C(/C=CC(O)=O)O
Clinical Information
– Phase 3
Research Area
– Neurological Disease
Solubility
– DMSO : 50 mg/mL (ultrasonic)|H2O : 10 mg/mL (ultrasonic)
Target
– Dopamine Receptor
Isoform
– D2 Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
