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SU14813 (maleate)
$84 – $312
Products Details
Product Description
– SU14813 maleate is a multi-targeted receptor tyrosine kinases inhibitor with IC50s of 50, 2, 4, 15 nM for VEGFR2, VEGFR1, PDGFRβ and KIT.
Web ID
– HY-10501A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C27H31FN4O8
References
– [1]Patyna S, et al. SU14813: a novel multiple receptor tyrosine kinase inhibitor with potent antiangiogenic and antitumor activity. Mol Cancer Ther. 2006 Jul;5(7):1774-82.
CAS Number
– 849643-15-8
Molecular Weight
– 558.56
Compound Purity
– 99.04
SMILES
– O=C(NC[C@@H](CN1CCOCC1)O)C2=C(NC(/C=C3C(NC4=C3C=C(C=C4)F)=O)=C2C)C.O=C(/C=CC(O)=O)O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 66.67 mg/mL (ultrasonic)
Target
– c-Kit;PDGFR;VEGFR
Isoform
– PDGFRβ;VEGFR1/Flt-1;VEGFR2/KDR/Flk-1
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
