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STAT3-IN-12
$150 – $1,550
Products Details
Product Description
– STAT3-IN-12 is a potent STAT3 signal inhibitor that can inhibit IL-6 induced JAK/STAT3 signalling pathway activation. STAT3-IN-12 inhibits cancer cell growth, migration, and induce cell apoptosis as well as cycle arrest. STAT3-IN-12 can be used in cancer-related research, such as hepatocellular carcinoma (HCC) and oesophageal carcinoma[1].
Web ID
– HY-150538
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C28H30N4O2
References
– [1]Yi-Chen Liu, et al. Benzobis(imidazole) derivatives as STAT3 signal inhibitors with antitumor activity.
Molecular Weight
– 454.56
Compound Purity
– 99.92
SMILES
– CCCN1C2=C(C=C3C(N(CCC)C(C4=CC=CC(OC)=C4)=N3)=C2)N=C1C5=CC=CC(OC)=C5
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Apoptosis;STAT
Isoform
– STAT3
Pathway
– Apoptosis;JAK/STAT Signaling;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
