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(S,R,S)-AHPC-phenol-C4-NH2 (dihydrochloride)
$120 – $1,040
Products Details
Product Description
– (S,R,S)-AHPC-phenol-C4-NH2 (VH032-phenol-C4-NH2) dihydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used in PROTAC technology[1].
Web ID
– HY-136184
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C28H43Cl2N5O5S
References
– [1][3].Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.|[2]Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019;17:160-176. Published 2019 Jan 25.
CAS Number
– 2376990-26-8
Molecular Weight
– 632.64
Compound Purity
– 99.01
SMILES
– [H]Cl.[H]Cl.CC(N[C@H](C(N1C[C@@H](C[C@H]1C(NCC2=CC=C(C=C2OCCCCN)C3=C(N=CS3)C)=O)O)=O)C(C)(C)C)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– E3 Ligase Ligand-Linker Conjugates
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
