(S,R,S)-AHPC-PEG2-NH2 hydrochloride

SKU T17924-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 53 CAD through 171 CAD

Products Details

Product Description

– (S,R,S)-AHPC-PEG2-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 6) is a synthesized E3 ligase ligand-linker conjugate that includes the (S,R,S)-AHPC based VHL ligand and a 2-unit PEG linker used in the synthesis of PROTAC.

Web ID

– T17924

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C28H42ClN5O6S

References

– Chan KH, et al. Impact of Target Warhead and Linkage Vector on Inducing Protein Degradation: Comparison of Bromodomain and Extra-Terminal (BET) Degraders Derived from Triazolodiazepine (JQ1) and Tetrahydroquinoline (I-BET726) BET Inhibitor Scaffolds. J Med Chem. 2018 Jan 25;61(2):504-513.

CAS Number

– 2097973-72-1

Molecular Weight

– C28H42ClN5O6S

Compound Purity

– 0.9929

SMILES

– O=C([C@H]1N(C([C@@H](NC(COCCOCCN)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2.Cl

Target

– Others

Pathway

– PROTAC

Product type

– PROTAC

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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