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(S,R,S)-AHPC-Me-decanedioic acid
SKU
HY-132938-Get quote
Category Reference compound
Tags Cancer, E3 Ligase Ligand-Linker Conjugates, PROTAC
Products Details
Product Description
– (S,R,S)-AHPC-Me-decanedioic acid is an E3 ligase ligand-linker conjugate that can be used in the synthesis of PROTACs.
Web ID
– HY-132938
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C33H48N4O6S
References
– [1]Pal P, et al. Discovery of a Novel BCL-XL PROTAC Degrader with Enhanced BCL-2 Inhibition. J Med Chem. 2021 Oct 14;64(19):14230-14246.
CAS Number
– 2380273-45-8
Molecular Weight
– 628.82
SMILES
– OC(CCCCCCCCC(N[C@H](C(N1C[C@@H](C[C@H]1C(N[C@@H](C)C2=CC=C(C=C2)C3=C(N=CS3)C)=O)O)=O)C(C)(C)C)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– E3 Ligase Ligand-Linker Conjugates
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.