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(S,R,S)-AHPC-Me-C7 ester
$750 – $1,180
Products Details
Product Description
– (S,R,S)-AHPC-Me-C7 ester is a E3 ligase ligand-linker conjugate used to synthesise BCL-XL PROTAC degraders[1].
Web ID
– HY-130640
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C32H46N4O6S
References
– [1]Khan S, et al. A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity. Nat Med. 2019 Dec;25(12):1938-1947.
CAS Number
– 2639528-48-4
Molecular Weight
– 614.80
Compound Purity
– 95.49
SMILES
– O=C([C@@H](NC(CCCCCC(OCC)=O)=O)C(C)(C)C)N1[C@H](C(N[C@@H](C)C2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@H](C1)O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 6.67 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– E3 Ligase Ligand-Linker Conjugates
Isoform
– Bcl-xL
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
