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(S,R,S)-AHPC-C7-amine
SKU
HY-136186-Get quote
Category Reference compound
Tags Cancer, E3 Ligase Ligand-Linker Conjugates, PROTAC
Products Details
Product Description
– (S,R,S)-AHPC-C7-amine (VH032-C7-amine) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for estrogen-related receptor α (ERRα) PROTAC degrader[1].
Web ID
– HY-136186
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C30H45N5O4S
References
– [1]Lijie Peng, et al. Identification of New Small-Molecule Inducers of Estrogen-related Receptor α (ERRα) Degradation. ACS Med Chem Lett. 2019 Apr 12;10(5):767-772.
CAS Number
– 2306389-04-6
Molecular Weight
– 571.77
SMILES
– O=C([C@H]1N(C([C@@H](NC(CCCCCCCN)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– E3 Ligase Ligand-Linker Conjugates
Isoform
– von Hippel-Lindau (VHL)
Pathway
– PROTAC
Product type
– Reference compound
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