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Products Details
Product Description
– SRE-II, an amide derivative, is an activatable photosensitizer for photodynamic cancer research with decreased fluorescence and photosensitizing capabilities. SRE-II can be further converted into the active photosensitizer SDU Red via carboxylesterase-catalyzed amide bond cleavage. SRE-II induces DNA damage and cell apoptosis in the presence of light. SRE-II can act as a promising theranostic agent for triple-negative breast cancer[1].
Web ID
– HY-155070
Shipping
– Room temperature
Molecular Formula
– C15H9ClINO2
References
– [1]Qiaoyun Jiang, et al. Lysosome-targeting phenalenones as efficient type I/II photosensitizers for anticancer photodynamic therapy. Eur J Med Chem. 2023 Jul 5;255:115418.
Molecular Weight
– 397.59
SMILES
– O=C(C=C1)C2=CC=CC3=C(NC(CCl)=O)C(I)=CC1=C32
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;DNA/RNA Synthesis
Pathway
– Apoptosis;Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
