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Product Description
– SPDB-DM4 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications, employing the maytansine-based payload DM4 (a tubulin inhibitor) connected through a SPDB linker. This compound demonstrates significant anti-tumor efficacy.
Web ID
– T18701
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C46H63ClN4O14S2
References
– Puja Sapra, et al. Investigational antibody drug conjugates for solid tumors. Expert Opin Investig Drugs. 2011 Aug;20(8):1131-49.
CAS Number
– 1626359-62-3
Molecular Weight
– C46H63ClN4O14S2
SMILES
– [H][C@@]12C[C@@](O)(NC(=O)O1)[C@]([H])(OC)C=C/C=C(C)Cc1cc(OC)c(Cl)c(c1)N(C)C(=O)C[C@H](OC(=O)[C@H](C)N(C)C(=O)CCC(C)(C)SSCCCC(=O)ON1C(=O)CCC1=O)[C@]1(C)O[C@H]1[C@@H]2C
Target
– Others
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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