Download Files:
Products Details
Product Description
– SOS1-IN-9 is a potent SOS1 inhibitor with an IC50 of 116.5 nM for SOS1-KRAS G12C (WO2022028506A1, compound 302)[1].
Web ID
– HY-144207
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C22H28F3N5O
References
– [1]Sos1 inhibitor, pharmaceutical composition containing same, and use therefor. WO2022028506A1.
CAS Number
– 2758900-76-2
Molecular Weight
– 435.49
SMILES
– CC1=NC(N[C@@H](C2=CC(N)=CC(C(F)(F)F)=C2)C)=C3CN(CCC3=N1)C4CCOCC4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ras
Isoform
– K-Ras
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
